| 2019, July 5 | 7.1 | Ridgecrest | 35.77 | -117.60 | 1 dead; preliminary estimate of economic losses $1 billion to $5 billion. Preceded by M6.4 foreshock on July 4.
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| 2016, December 8 | 6.5 | Ferndale Offshore | 40.48 | -126.15 | |
| 2014, August 24 | 6.0 | South Napa | 38.22 | -122.31 | 2 dead; total economic losses estimated at $443 million to $800 million |
| 2014, March 9 | 6.8 | Ferndale | 40.83 | -125.13 | |
| 2010, April 4 | 7.2 | Calexico | 32.26 | -115.29 | |
| 2010, January 9 | 6.5 | Ferndale | 40.65 | -124.76 | |
| 2003, December 22 | 6.5 | San Simeon | 35.71 | -121.10 | |
| 1999, October 16 | 7.1 | Bullion Mountains (Hector Mine) | 34.60 | -116.27 | Minimal injuries and damage due to sparse population in affected area |
| 1994, September 1 | 7.0 | Offshore, about 70 miles W of Cape Mendocino | 40.40 | -125.68 | |
| 1994, January 17 | 6.7 | Northridge | 34.21 | -118.54 | 57 dead; more than 9,000 injured; about $40 billion in property damage |
| 1992, June 28 | 7.3 | Landers | 34.20 | -116.44 | 1 dead; 402 injured; $91.1 million in property damage |
| 1992, June 28 | 6.5 | Big Bear | 34.17 | -116.83 | Included with Landers losses, above |
| 1992, April 26 | 6.6 | Petrolia | 40.43 | -124.60 | Aftershock of the April 25 quake |
| 1992, April 26 | 6.6 | Petrolia | 40.38 | -124.59 | Another aftershock of April 25 quake |
| 1992, April 25 | 7.2 | Petrolia | 40.33 | -124.23 | 356 injured; $48.3 million in property damage |
| 1991, August 17 | 7.0 | Offshore, about 100 miles NW of Eureka | 41.71 | -125.63 | Preceded by two quakes (M6.3 and M6.2) on August 16 and 17
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| 1991, July 12 | 6.6 | Offshore west of Crescent City | 42.02 | -125.72 | |
| 1989, October 17 | 6.9 | Loma Prieta | 37.04 | -121.88 | 63 dead; 3,737 injured; $6 billion in property damage |
| 1987, November 24 | 6.2 | Superstition Hills | 33.09 | -115.79 | $3 million in property damage |
| 1987, November 24 | 6.6 | Superstition Hills | 33.01 | -115.85 | Included with losses reported above |
| 1987, October 1 | 6.0 | Whittier Narrows | 34.07 | -118.08 | 8 dead; $358 million in property damage to 10,500 homes and businesses |
| 1986, July 21 | 6.4 | Chalfant Valley | 37.54 | -118.44 | $2.7 million in property damage |
| 1984, April 24 | 6.2 | Morgan Hill | 37.31 | -121.68 | $8 million in property damage |
| 1983, May 2 | 6.4 | Coalinga | 36.23 | -120.31 | |
| 1980, November 8 | 7.4 | West of Eureka | 41.12 | -124.67 | 6 injured; $2 million in property damage |
| 1980, May 25 | 6.3 | Mammoth Lakes | 37.60 | -118.85 | 9 injured; $2 million in property damage |
| 1979, October 15 | 6.5 | Imperial Valley | 32.61 | -115.32 | 9 injured; $30 million in property damage |
| 1976, November 26 | 6.8 | Offshore, about 100 mi WNW of Eureka | 41.29 | -125.71 | |
| 1971, February 9 | 6.6 | San Fernando | 34.41 | -118.40 | 65 dead; more than 2,000 injured; $505 million in losses |
| 1968, April 8 | 6.6 | Borrego Mountain | 33.19 | -116.13 | |
| 1956, February 9 | 6.5 | In Mexico, about 80 miles SW of El Centro | 31.75 | -115.92 | |
| 1954, December 21 | 6.6 | East of Arcata | 40.93 | -123.78 | 1 dead; several injured; $2.1 million in property damage |
| 1954, December 16 | 7.3 | Fairview Peak, near Fallon, NV | 39.28 | -118.12 | |
| 1954, December 16 | 7.1 | Dixie Valley, near Fallon, NV | 39.80 | -118.10 | |
| 1954, August 24 | 6.8 | Rainbow Mountain, near Fallon, NV | 39.58 | -118.45 | |
| 1954, July 6 | 6.8 | Rainbow Mountain, near Fallon, NV | 39.42 | -118.53 | |
| 1952, July 21 | 7.3 | Kern County earthquake | 35.00 | -119.02 | 12 dead; $60 million in property damage |
| 1947, April 10 | 6.5 | East of Yermo | 34.98 | -116.55 | |
| 1942, October 21 | 6.6 | West of Westmorland | 32.97 | -116.00 | |
| 1941, February 9 | 6.6 | Offshore, about 65 miles W of Eureka | 40.70 | -125.40 | |
| 1940, May 19 | 7.0 | Imperial Valley | 32.73 | -115.50 | 9 dead; $6 million in property damage |
| 1934, December 31 | 7.0 | In Mexico, about 100 miles SE of El Centro | 32.00 | -114.75 | |
| 1934, December 30 | 6.5 | In Mexico, about 40 miles S of El Centro | 32.25 | -115.50 | |
| 1934, July 6 | 6.5 | Offshore, about 100 mi WNW of Eureka | 41.25 | -125.75 | |
| 1933, March 11 | 6.4 | Long Beach | 33.70 | -118.00 | 115 dead; $40 million in property damage |
| 1932, December 21 | 7.2 | Cedar Mountain, near Gabbs, NV | 38.75 | -118.00 | |
| 1927, November 4 | 7.1 | 40 km west of Lompoc | 34.60 | -120.90 | Damage in Santa Barbara and San Luis Obispo counties |
| 1925, June 29 | 6.8 | Santa Barbara | 34.30 | -119.80 | 13 dead; $8 million in property damage |
| 1923, January 22 | 7.2 | Off Cape Mendocino | 40.40 | -124.90 | Destructive in Humboldt County; strongly felt in Reno |
| 1922, January 31 | 7.3 | Offshore, about 70 mi W of Eureka | 41.00 | -125.50 | |
| 1918, July 15 | 6.5 | Offshore, about 40 W of Eureka | 41.00 | -125.00 | |
| 1918, April 21 | 6.8 | San Jacinto | 33.75 | -117.00 | 1 dead; several injuries; $200,000 in property damage |
| 1915, November 21 | 6.6 | In Mexico, about 60 miles S of El Centro | 32.00 | -115.00 | |
| 1911, July 1 | 6.6 | Morgan Hill area | 37.25 | -121.75 | |
| 1906, April 18 | 7.8 | Great 1906 San Francisco Earthquake and Fire | 37.70 | -122.50 | 3,000 dead; $524 million in property damage (includes damage from fire) |
| 1899, December 25 | 6.7 | San Jacinto and Hemet | 33.80 | -117.00 | 6 dead; $50,000 in property damage |
| 1899, July 22 | 6.4 | Wrightwood | 34.30 | -117.50 | Chimneys knocked down; landslides reported |
| 1899, April 16 | 7.0 | Offshore, about 80 miles west of Eureka | 41.00 | -125.80 | |
| 1898, April 15 | Uncertain; 6.7 estimated | Fort Bragg - Mendocino | 39.20 | -123.80 | Damage from Fort Bragg to Mendocino; 3 houses collapsed; landslides reported |
| 1898, March 31 | 6.4 | Mare Island | 38.20 | -122.50 | $350,000 in property damage |
| 1892, April 19 | 6.6 | Vacaville | 38.40 | -122.00 | 1 dead; $225,000 in property damage |
| 1892, February 24 | 7.3 | Laguna Salida, Baja California | 32.55 | -115.65 | Damage to San Diego and Imperial Valley |
| 1890, February 9 | 6.8 | Uncertain; San Jacinto fault suspected | 33.40 | -116.30 | Little damage |
| 1873, November 23 | 6.9 | Crescent City region | 42.00 | -124.20 | Damage in California-Oregon border area |
| 1872, March 26 | 7.4 | Owens Valley | 36.70 | -118.10 | 27 dead; 56 injured; $250,000 in property damage |
| 1872, March 26 | 6.8 | Owens Valley | 36.90 | -118.20 | Aftershock of previous entry |
| 1872, April 11 | 6.8 | Owens Valley | 37.50 | -118.50 | Aftershock of March 26, 1872 quake |
| 1868, October 21 | 7.0 | Hayward Fault | 37.70 | -122.10 | 30 dead; $350,000 in property damage |
| 1865, October 8 | 6.5 | Santa Cruz Mountains | 37.20 | -121.90 | $0.5 million in property damage |
| 1860, March 15 | Uncertain; 6.5 estimated | Carson City | 39.50 | -119.50 | |
| 1857, January 9 | 7.9 | Great Fort Tejon earthquake | 36.20 | -120.80 | 1 dead; damage from Monterey to San Bernardino County |
| 1852, November 29 | Uncertain; 6.5 estimated | Near Fort Yuma, Arizona | 32.50 | -115 | |
| 1838, June | Uncertain; 7.4 estimated | San Francisco to San Juan Bautista | 37.30 | -122.15 | Damage to San Francisco and Santa Clara |
| 1836, June 10 | Uncertain; 6.4 estimated | Near San Juan Bautista | 36.90 | -121.50 | [Older reports reported this quake as possibly larger and centered near Oakland] |
| 1812, December 21 | Uncertain; 7.1 estimated | Los Angeles, Ventura, Santa Barbara | 34.75 | -118.60 | 1 dead |
| 1812, December 8 | Uncertain; 7.3 estimated | Wrightwood | 34.37 | -117.65 | 40 dead at San Juan Capistrano |
| 1800, November 22 | Uncertain; 6.3 estimated | San Diego and San Juan Capistrano region | 32.90 | -117.80 | Damaged adobe walls of missions in San Diego and San Juan Capistrano |
| 1700, January 26 | Uncertain; 9.0 estimated | Offshore, somewhere between Cape Mendocino and Canada | Unknown | Unknown | Data not available, but it shook Northern California, Oregon, Washington, and southern British Columbia; caused tsunami damage to villages in Japan and western United States
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